Ontology highlight
ABSTRACT:
SUBMITTER: Lin L
PROVIDER: S-EPMC6162292 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Lin Luan L Chen Quan Q Hirsch Jeanne P JP Yoo Seungyeul S Yeung Kayee K Bumgarner Roger E RE Tu Zhidong Z Schadt Eric E EE Zhu Jun J
Nature communications 20180928 1
A large amount of panomic data has been generated in populations for understanding causal relationships in complex biological systems. Both genetic and temporal models can be used to establish causal relationships among molecular, cellular, or phenotypical traits, but with limitations. To fully utilize high-dimension temporal and genetic data, we develop a multivariate polynomial temporal genetic association (MPTGA) approach for detecting temporal genetic loci (teQTLs) of quantitative traits mon ...[more]