Ontology highlight
ABSTRACT:
SUBMITTER: Angeles AK
PROVIDER: S-EPMC6164491 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Angeles Arlou Kristina AK Bauer Simone S Ratz Leonie L Klauck Sabine M SM Sültmann Holger H
Diagnostics (Basel, Switzerland) 20180902 3
In the past decade, multi-national and multi-center efforts were launched to sequence prostate cancer genomes, transcriptomes, and epigenomes with the aim of discovering the molecular underpinnings of tumorigenesis, cancer progression, and therapy resistance. Multiple biological markers and pathways have been discovered to be tumor drivers, and a molecular classification of prostate cancer is emerging. Here, we highlight crucial findings of these genome-sequencing projects in localized and advan ...[more]