Drug Repurposing of Metabolic Agents in Malignant Glioma.
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ABSTRACT:
SUBMITTER: Seliger C
PROVIDER: S-EPMC6164672 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Publications
Drug Repurposing of Metabolic Agents in Malignant Glioma.
International journal of molecular sciences 20180914 9
Gliomas are highly invasive brain tumors with short patient survival. One major pathogenic factor is aberrant tumor metabolism, which may be targeted with different specific and unspecific agents. Drug repurposing is of increasing interest in glioma research. Drugs interfering with the patient's metabolism may also influence glioma metabolism. In this review, we outline definitions and methods for drug repurposing. Furthermore, we give insights into important candidates for a metabolic drug repu ...[more]
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