Novel photoactivatable substrates for Renilla luciferase imaging in vitro and in vivo.
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ABSTRACT:
SUBMITTER: Zhang C
PROVIDER: S-EPMC6165844 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Publications
Novel photoactivatable substrates for Renilla luciferase imaging in vitro and in vivo.
Zhang Chaochao C Cheng Lin L Dong Gaopan G Han Guangxi G Yang Xingye X Tang Chunchao C Li Xiang X Zhou Yubin Y Du Lupei L Li Minyong M
Organic & biomolecular chemistry 20180701 26
To develop a photoactivatable bioluminescence imaging technique, a set of high and efficient photoactivatable substrates for Renilla luciferase has been well designed and synthesized. Surprisingly, all of them could release the free luciferin that presented robust bioluminescent signals ex vivo and in living animals after UV irradiation at 365 nm. ...[more]
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