Ontology highlight
ABSTRACT:
SUBMITTER: Wiezel GA
PROVIDER: S-EPMC6166653 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Wiezel Gisele A GA dos Santos Patty K PK Cordeiro Francielle A FA Bordon Karla C F KC Selistre-de-Araújo Heloisa S HS Ueberheide Beatrix B Arantes Eliane C EC
Toxicon : official journal of the International Society on Toxinology 20150831 Pt B
Hyaluronidases contribute to local and systemic damages after envenoming, since they act as spreading factors cleaving the hyaluronan presents in the connective tissues of the victim, facilitating the diffusion of venom components. Although hyaluronidases are ubiquitous in snake venoms, they still have not been detected in transcriptomic analysis of the Lachesis venom gland and neither in the proteome of its venom performed previously. This work purified a hyaluronidase from Lachesis muta rhombe ...[more]