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Detection and genetic characterization of porcine circovirus 3 from aborted fetuses and pigs with respiratory disease in Korea.

ABSTRACT: A novel porcine circovirus 3 (PCV3) was first detected in pigs showing porcine dermatitis and nephropathy syndrome, reproductive failure, and multisystemic inflammation in the USA. Herein, we report on PCV3 as a potential etiological agent of clinical signs, reproductive failure and respiratory distress on Korean pig farms, based on in situ hybridization, pathological, and molecular findings. Confirmation of the presence of PCV3 may increase co-infection with other causative agents of disease in Korean pig herds, indicating the need for further systemic investigation of pathogenicity and of multiple infections with PCV2 genotypes and bacteria, and the development of an effective PCV3 vaccine.

SUBMITTER: Kim SH

PROVIDER: S-EPMC6167340 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Detection and genetic characterization of porcine circovirus 3 from aborted fetuses and pigs with respiratory disease in Korea.

Kim Seong-Hee SH Park Ji-Young JY Jung Ji-Youl JY Kim Ha-Young HY Park Yu-Ri YR Lee Kyoung-Ki KK Lyoo Young S YS Yeo Sang-Geon SG Park Choi-Kyu CK

Journal of veterinary science 20180901 5

A novel porcine circovirus 3 (PCV3) was first detected in pigs showing porcine dermatitis and nephropathy syndrome, reproductive failure, and multisystemic inflammation in the USA. Herein, we report on PCV3 as a potential etiological agent of clinical signs, reproductive failure and respiratory distress on Korean pig farms, based on <i>in situ</i> hybridization, pathological, and molecular findings. Confirmation of the presence of PCV3 may increase co-infection with other causative agents of dis ...[more]

PMID: 30041289

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