Rfoot: Transcriptome-Scale Identification of RNA-Protein Complexes from Ribosome Profiling Data.
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ABSTRACT:
SUBMITTER: Ji Z
PROVIDER: S-EPMC6168344 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Rfoot: Transcriptome-Scale Identification of RNA-Protein Complexes from Ribosome Profiling Data.
Current protocols in molecular biology 20180831 1
Ribosome profiling was developed to identify genome-wide RNA fragments associated with translating ribosomes. However, no experimental procedure was developed to effectively purify ribosome-RNA complexes. Actually, ribosome profiling is a transcriptomic RNase footprinting assay, which can identify both ribosomal and non-ribosomal protein-RNA complexes. Many sequencing reads represent functional RNA footprints associated with non-ribosomal proteins. Here I present a computational pipeline named R ...[more]
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