Computerised Dynamic Posturography in Premanifest and Manifest individuals with Huntington's Disease.
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ABSTRACT:
SUBMITTER: Reyes A
PROVIDER: S-EPMC6168504 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Computerised Dynamic Posturography in Premanifest and Manifest individuals with Huntington's Disease.
Reyes Alvaro A Salomonczyk Danielle D Teo Wei-Peng WP Medina Luis D LD Bartlett Danielle D Pirogovsky-Turk Eva E Zaenker Pauline P Bloom Jody Corey JC Simmons Roger W RW Ziman Mel M Gilbert Paul E PE Cruickshank Travis T
Scientific reports 20181002 1
Evidence from small-scale studies indicates that impairments in postural stability are an early and disabling feature of Huntington's disease (HD) and may be a useful clinical endpoint for disease modifying trials. Larger studies are needed to confirm these preliminary findings and the suitability of postural stability outcomes as clinical endpoints. Static and dynamic postural stability were evaluated in 54 premanifest HD, 36 manifest HD and 45 healthy individuals using the Sensory Organization ...[more]
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