Unknown

Dataset Information

0

Clinical value of bioelectrical properties of cancerous tissue in advanced epithelial ovarian cancer patients.

ABSTRACT: Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC). In this study, we suggest that profiling of tumour parameters such as bioelectrical-potential and metabolites, detectable by electronic sensors, could facilitate the future development of devices to better monitor disease and predict surgical and treatment outcomes. Biopotential was recorded, using a potentiometric measurement system, in ex vivo paired non-cancerous and cancerous omental tissues from advanced stage EOC (n?=?36), and lysates collected for metabolite measurement by microdialysis. Consistently different biopotential values were detected in cancerous tissue versus non-cancerous tissue across all cases (p?

SUBMITTER: Cunnea P 

PROVIDER: S-EPMC6168525 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC). In this study, we suggest that profiling of tumour parameters such as bioelectrical-potential and metabolites, detectable by electronic sensors, could facilitate the future development of devices to better monitor disease and predict surgical and treatment outcomes. Biopotential was recorded, using  ...[more]

Similar Datasets

Transcriptomics microRNA alterations associated to clinical response in advanced stage ovarian cancer patients
2012-03-09 | E-GEOD-25204 | biostudies-arrayexpress
Genomics microRNA alterations associated to clinical response in advanced stage ovarian cancer patients
2012-03-09 | GSE25204 | GEO
Transcriptomics microRNA alterations associated to clinical response in advanced stage ovarian cancer patients (test set)
2012-03-09 | E-GEOD-25203 | biostudies-arrayexpress
Transcriptomics microRNA alterations associated to clinical response in advanced stage ovarian cancer patients (training set)
2012-03-09 | E-GEOD-25202 | biostudies-arrayexpress
Genomics microRNA alterations associated to clinical response in advanced stage ovarian cancer patients (test set)
2012-03-09 | GSE25203 | GEO
Genomics microRNA alterations associated to clinical response in advanced stage ovarian cancer patients (training set)
2012-03-09 | GSE25202 | GEO
Unknown Predictive value of the Age-Adjusted Charlson Comorbidity Index on perioperative complications and survival in patients undergoing primary debulking surgery for advanced epithelial ovarian cancer.
| S-EPMC4972341 | biostudies-literature
Unknown Hepatobiliary Disease Resection in Patients with Advanced Epithelial Ovarian Cancer: Prognostic Role and Optimal Cytoreduction.
| S-EPMC7752869 | biostudies-literature
Unknown Detection of Abundant Non-Haematopoietic Circulating Cancer-Related Cells in Patients with Advanced Epithelial Ovarian Cancer.
| S-EPMC6678489 | biostudies-literature
Unknown Latest research and treatment of advanced-stage epithelial ovarian cancer.
| S-EPMC3786558 | biostudies-literature