Dataset Information

The etiology of potential small-bowel bleeding depending on patient's age and gender.

ABSTRACT:

Background

Whether the etiology of potential small-bowel bleeding depends on the age and gender of the patient is not yet fully understood.

Methods

A total of 1953 patients who underwent video capsule endoscopy (VCE) to evaluate potential small-bowel bleeding and were registered in the Capsule Endoscopy Nationwide Database Registry from 2003 to 2014 were eligible for this study. VCE findings and the etiology of small-bowel bleeding were analyzed by age and gender.

Results

The diagnostic yield of VCE was 48.4% (95% CI: 46.2%-50.6%) and the diagnosis rate of etiology of potential small-bowel bleeding was 61.4% (95% CI: 59.2%-63.6%). The etiology of potential small-bowel bleeding depends on the age and gender of the patient. Crohn's disease and small-bowel diverticular diseases were more prevalent etiology of potential small-bowel bleeding in the young adults group (p<0.00152) by Bonferroni correction.

Conclusions

The etiology of potential small-bowel bleeding depends on the age of the patient. Thus, an individualized lesion-specific diagnostic approach based on age might be needed for patients with potential small-bowel bleeding.

SUBMITTER: Song JH

PROVIDER: S-EPMC6169048 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Publications

The etiology of potential small-bowel bleeding depending on patient's age and gender.

Song Joo Hye JH Hong Sung Noh SN Kyung Chang Dong D Ran Jeon Seong S Kim Jin-Oh JO Kim Jinsu J Lee Bo-In BI Choi Myung-Gyu MG Kim Kyeong Ok KO Yang Dong-Hoon DH Song Hyun Joo HJ Hyuk Do Jae J Jeong Lim Yun Y Shim Ki-Nam KN Park Soo Jung SJ Kim Ji Hyun JH Moon Jeong Seop JS Joo Jang Hyun H Jai Chun Hoon H

United European gastroenterology journal 20180930 8

<h4>Background</h4>Whether the etiology of potential small-bowel bleeding depends on the age and gender of the patient is not yet fully understood.<h4>Methods</h4>A total of 1953 patients who underwent video capsule endoscopy (VCE) to evaluate potential small-bowel bleeding and were registered in the Capsule Endoscopy Nationwide Database Registry from 2003 to 2014 were eligible for this study. VCE findings and the etiology of small-bowel bleeding were analyzed by age and gender.<h4>Results</h4>T ...[more]

PMID: 30288279

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Project description:Patients with cirrhosis have significant physical, psychological, and practical needs. We documented patients' perceived need for support with these issues and the differences with increasing liver disease severity, etiology, and age. Using the supportive needs assessment tool for cirrhosis (SNAC), we examined the rate of moderate-to-high unmet needs (Poisson regression; incidence rate ratio [IRR]) and the correlation between needs and sociodemographic/clinical characteristics (multivariable linear regression) in 458 Australians adults with cirrhosis. Primary liver disease etiology was alcohol in 37.6% of patients, chronic viral hepatitis C in 25.5%, and nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) in 23.8%. A total of 64.6% of patients had Child-Pugh class A cirrhosis. Most patients (81.2%) had at least one moderate-to-high unmet need item; more than 25% reported a moderate-to-high need for help with "lack of energy," "sleep poorly," "feel unwell," "worry about … illness getting worse (liver cancer)," "have anxiety/stress," and "difficulty with daily tasks." Adjusting for key sociodemographic/clinical factors, patients with Child-Pugh C had a greater rate of "practical and physical needs" (vs. Child-Pugh A; IRR = 2.94, 95% confidence interval [CI] 2.57-3.37), patients with NAFLD/NASH had a greater rate of needs with "lifestyle changes" (vs. alcohol; IRR = 1.81, 95% CI 1.18-2.77) and "practical and physical needs" (IRR = 1.43, 95% CI 1.23-1.65), and patients aged ≥65 years had fewer needs overall (vs. 18-64 years; IRR = 0.70, 95% CI 0.64-0.76). Higher overall SNAC scores were associated with Child-Pugh B and C (both P < 0.001), NAFLD/NASH (P = 0.028), patients with "no partner, do not live alone" (P = 0.004), unemployment (P = 0.039), ascites (P = 0.022), and dyslipidemia (P = 0.024) compared with their counterparts. Conclusion: Very high levels of needs were reported by patients with cirrhosis. This information is important to tailor patient-centered care and facilitate timely interventions or referral to support services.

Dataset Information

The etiology of potential small-bowel bleeding depending on patient's age and gender.

Background

Methods

Results

Conclusions

Publications

The etiology of potential small-bowel bleeding depending on patient's age and gender.

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