Gene Coexpression Network Comparison via Persistent Homology.
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ABSTRACT:
SUBMITTER: Duman AN
PROVIDER: S-EPMC6169238 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Gene Coexpression Network Comparison via Persistent Homology.
Duman Ali Nabi AN Pirim Harun H
International journal of genomics 20180919
Persistent homology, a topological data analysis (TDA) method, is applied to microarray data sets. Although there are a few papers referring to TDA methods in microarray analysis, the usage of persistent homology in the comparison of several weighted gene coexpression networks (WGCN) was not employed before to the very best of our knowledge. We calculate the persistent homology of weighted networks constructed from 38 Arabidopsis microarray data sets to test the relevance and the success of this ...[more]
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