Ontology highlight
ABSTRACT:
SUBMITTER: Rzechonek DA
PROVIDER: S-EPMC6170386 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Rzechonek Dorota A DA Day Alison M AM Quinn Janet J Mirończuk Aleksandra M AM
Scientific reports 20181003 1
Erythritol production is a unique response to hyperosmotic stress that is observed in a small group of yeasts, including Yarrowia lipolytica. This study investigated whether this unusual mechanism is regulated by the HOG pathway, well described in Saccharomyces cerevisiae. The gene YALI0E25135g was identified as the Y. lipolytica homologue of HOG1 and was found to be phosphorylated in response to hyperosmotic shock. Deletion of the gene caused a significant decrease in resistance to hyperosmotic ...[more]