Ontology highlight
ABSTRACT:
SUBMITTER: Wood DJ
PROVIDER: S-EPMC6170502 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Wood Daniel J DJ Endicott Jane A JA
Open biology 20180901 9
Since their characterization as conserved modules that regulate progression through the eukaryotic cell cycle, cyclin-dependent protein kinases (CDKs) in higher eukaryotic cells are now also emerging as significant regulators of transcription, metabolism and cell differentiation. The cyclins, though originally characterized as CDK partners, also have CDK-independent roles that include the regulation of DNA damage repair and transcriptional programmes that direct cell differentiation, apoptosis a ...[more]