Ontology highlight
ABSTRACT:
SUBMITTER: Woodard J
PROVIDER: S-EPMC6170596 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Woodard Jaie J Srivastava Kinshuk R KR Rahamim Gil G Grupi Asaf A Hogan Steven S Witalka David J DJ Nawrocki Grzegorz G Haas Elisha E Feig Michael M Lapidus Lisa J LJ
Biophysical journal 20180827 7
Intramolecular protein diffusion, the motion of one part of the polypeptide chain relative to another part, is a fundamental aspect of protein folding and may modulate amyloidogenesis of disease-associated intrinsically disordered proteins. Much work has determined such diffusion coefficients using a variety of probes, but there has been an apparent discrepancy between measurements using long-range probes, such as fluorescence resonance energy transfer, and short-range probes, such as Trp-Cys qu ...[more]