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ABSTRACT: Background
Movement disorders associated with exposure to antipsychotic drugs are common and stigmatising but underdiagnosed.Aims
To develop and evaluate a new clinical procedure, the ScanMove instrument, for the screening of antipsychotic-associated movement disorders for use by mental health nurses.Method
Item selection and content validity assessment for the ScanMove instrument were conducted by a panel of neurologists, psychiatrists and a mental health nurse, who operationalised a 31-item screening procedure. Interrater reliability was measured on ratings for 30 patients with psychosis from ten mental health nurses evaluating video recordings of the procedure. Criterion and concurrent validity were tested comparing the ScanMove instrument-based rating of 13 mental health nurses for 635 community patients from mental health services with diagnostic judgement of a movement disorder neurologist based on the ScanMove instrument and a reference procedure comprising a selection of commonly used rating scales.Results
Interreliability analysis showed no systematic difference between raters in their prediction of any antipsychotic-associated movement disorders category. On criterion validity testing, the ScanMove instrument showed good sensitivity for parkinsonism (90%) and hyperkinesia (89%), but not for akathisia (38%), whereas specificity was low for parkinsonism and hyperkinesia, and moderate for akathisia.Conclusions
The ScanMove instrument demonstrated good feasibility and interrater reliability, and acceptable sensitivity as a mental health nurse-administered screening tool for parkinsonism and hyperkinesia.Declaration of interest
None.
SUBMITTER: Balint B
PROVIDER: S-EPMC6171333 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Balint Bettina B Killaspy Helen H Marston Louise L Barnes Thomas T Latorre Anna A Joyce Eileen E Clarke Caroline S CS De Micco Rosa R Edwards Mark J MJ Erro Roberto R Foltynie Thomas T Hunter Rachael M RM Nolan Fiona F Schrag Anette A Freemantle Nick N Foreshaw Yvonne Y Green Nicholas N Bhatia Kailash P KP Martino Davide D
BJPsych open 20180927 5
<h4>Background</h4>Movement disorders associated with exposure to antipsychotic drugs are common and stigmatising but underdiagnosed.<h4>Aims</h4>To develop and evaluate a new clinical procedure, the ScanMove instrument, for the screening of antipsychotic-associated movement disorders for use by mental health nurses.<h4>Method</h4>Item selection and content validity assessment for the ScanMove instrument were conducted by a panel of neurologists, psychiatrists and a mental health nurse, who oper ...[more]