CPhos: a program to calculate and visualize evolutionarily conserved functional phosphorylation sites.
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ABSTRACT:
SUBMITTER: Zhao B
PROVIDER: S-EPMC6171338 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Publications
CPhos: a program to calculate and visualize evolutionarily conserved functional phosphorylation sites.
Zhao Boyang B Pisitkun Trairak T Hoffert Jason D JD Knepper Mark A MA Saeed Fahad F
Proteomics 20121029 22
Profiling using high-throughput MS has discovered an overwhelming number of novel protein phosphorylation sites ("phosphosites"). However, the functional relevance of these sites is not always clear. In light of recent studies on the evolutionary mechanism of phosphorylation, we have developed CPhos, a Java program that can assess the conservation of phosphosites among species using an information theory-based approach. The degree of conservation established using CPhos can be used to assess the ...[more]
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