Dataset Information

An agent-based model of urban insurgence: Effect of gathering sites and Koopman mode analysis.

ABSTRACT: The paper investigates the effect of preferential gathering sites on urban insurgency in an agent-based model (ABM). The ABM model was proposed in earlier work and has been validated using FBI data. There is a nonlinear tradeoff between the local density of citizens due to the number of preferential gathering sites and the ability of law enforcement officers (LEOs) to adequately patrol that leads to a non-monotonic behavior in the number of large scale outburst of insurgency with respect to the number of gathering sites. The inclusion of a moderate number of sites decreases the number of large-scale outbursts. Having no gathering sites or a large number of gathering sites has a dilutive effect on the number of large-scale outbursts. Thus, this non-monotonicity indicates that a small number of organized units produces a larger insurgency effect than a larger number of distributed units. It is also shown, using Koopman mode analysis, that the spatial morphology of agents due to the gathering sites gives rise to temporal organization of the model dynamics; there is a prominent quasi-periodic component in the number of active and intimidated citizens and in the spatial distribution of the LEOs.

SUBMITTER: Fonoberova M

PROVIDER: S-EPMC6173437 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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An agent-based model of urban insurgence: Effect of gathering sites and Koopman mode analysis.

Fonoberova Maria M Mezić Igor I Mezić Jadranka J Mohr Ryan R

PloS one 20181005 10

The paper investigates the effect of preferential gathering sites on urban insurgency in an agent-based model (ABM). The ABM model was proposed in earlier work and has been validated using FBI data. There is a nonlinear tradeoff between the local density of citizens due to the number of preferential gathering sites and the ability of law enforcement officers (LEOs) to adequately patrol that leads to a non-monotonic behavior in the number of large scale outburst of insurgency with respect to the ...[more]

PMID: 30289939

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Project description:IntroductionParaspinal stereotactic body radiotherapy (SBRT) involves risks of severe complications. We evaluated the safety of the paraspinal SBRT program in a large academic hospital by applying failure modes and effects analysis.MethodsThe analysis was conducted by a multidisciplinary committee (two therapists, one dosimetrist, four physicists, and two radiation oncologists). The paraspinal SBRT workflow was segmented into four phases (simulation, treatment planning, delivery, and machine quality assurance (QA)). Each phase was further divided into a sequence of sub-processes. Potential failure modes (PFM) were identified from each subprocess and scored in terms of the frequency of occurrence, severity and detectability, and a risk priority number (RPN). High-risk PFMs were identified based on RPN and were studied for root causes using fault tree analysis.ResultsOur paraspinal SBRT process was characterized by eight simulations, 11 treatment planning, nine delivery, and two machine QA sub-processes. There were 18, 29, 19, and eight PFMs identified from simulation, planning, treatment, and machine QA, respectively. The median RPN of the PFMs was 62.9 for simulation, 68.3 for planning, 52.9 for delivery, and 22.0 for machine QA. The three PFMs with the highest RPN were: previous radiotherapy outside the institution is not accurately evaluated (RPN: 293.3), incorrect registration between diagnostic magnetic resonance imaging and simulation computed tomography causing incorrect contours (273.0), and undetected patient movement before ExacTrac baseline (217.8). Remedies to the high RPN failures were implemented, including staff education, standardized magnetic resonance imaging acquisition parameters, and an image fusion process, and additional QA on beam steering.ConclusionsA paraspinal SBRT workflow in a large clinic was evaluated using a multidisciplinary and systematic risk analysis, which led to feasible solutions to key root causes. Treatment planning was a major source of PFMs that systematically affect the safety and quality of treatments. Accurate evaluation of external treatment records remains a challenge.

Project description:To develop and implement a failure mode and effect analysis (FMEA)-based commissioning and quality assurance framework for dynamic multileaf collimator (DMLC) tumor tracking systems.A systematic failure mode and effect analysis was performed for a prototype real-time tumor tracking system that uses implanted electromagnetic transponders for tumor position monitoring and a DMLC for real-time beam adaptation. A detailed process tree of DMLC tracking delivery was created and potential tracking-specific failure modes were identified. For each failure mode, a risk probability number (RPN) was calculated from the product of the probability of occurrence, the severity of effect, and the detectibility of the failure. Based on the insights obtained from the FMEA, commissioning and QA procedures were developed to check (i) the accuracy of coordinate system transformation, (ii) system latency, (iii) spatial and dosimetric delivery accuracy, (iv) delivery efficiency, and (v) accuracy and consistency of system response to error conditions. The frequency of testing for each failure mode was determined from the RPN value.Failures modes with RPN > or = 125 were recommended to be tested monthly. Failure modes with RPN < 125 were assigned to be tested during comprehensive evaluations, e.g., during commissioning, annual quality assurance, and after major software/hardware upgrades. System latency was determined to be approximately 193 ms. The system showed consistent and accurate response to erroneous conditions. Tracking accuracy was within 3%-3 mm gamma (100% pass rate) for sinusoidal as well as a wide variety of patient-derived respiratory motions. The total time taken for monthly QA was approximately 35 min, while that taken for comprehensive testing was approximately 3.5 h.FMEA proved to be a powerful and flexible tool to develop and implement a quality management (QM) framework for DMLC tracking. The authors conclude that the use of FMEA-based QM ensures efficient allocation of clinical resources because the most critical failure modes receive the most attention. It is expected that the set of guidelines proposed here will serve as a living document that is updated with the accumulation of progressively more intrainstitutional and interinstitutional experience with DMLC tracking.

Dataset Information

An agent-based model of urban insurgence: Effect of gathering sites and Koopman mode analysis.

Publications

An agent-based model of urban insurgence: Effect of gathering sites and Koopman mode analysis.

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