Systemic Effects of Segmental Vibration in an Animal Model of Hand-Arm Vibration Syndrome.
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ABSTRACT:
SUBMITTER: Krajnak K
PROVIDER: S-EPMC6173648 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Systemic Effects of Segmental Vibration in an Animal Model of Hand-Arm Vibration Syndrome.
Krajnak Kristine K Waugh Stacy S
Journal of occupational and environmental medicine 20181001 10
<h4>Objective</h4>Epidemiology suggests that occupational exposure to hand-transmitted (segmental) vibration has local and systemic effects. This study used an animal model of segmental vibration to characterize the systemic effects of vibration.<h4>Methods</h4>Male Sprague Dawley rats were exposed to tail vibration for 10 days. Genes indicative of inflammation, oxidative stress, and cell cycle, along were measured in the heart, kidney, prostate, and liver.<h4>Results</h4>Vibration increased oxi ...[more]
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