Ontology highlight
ABSTRACT:
SUBMITTER: Chamoun K
PROVIDER: S-EPMC6174068 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Chamoun Kamal K Loghavi Sanam S Pemmaraju Naveen N Konopleva Marina M Kroll Michael M Nguyen-Cao Madeleine M Hornbaker Marisa M DiNardo Courtney D CD Kadia Tapan T Jorgensen Jeffrey J Andreeff Michael M Hu Shimin S Benton Christopher B CB
Experimental hematology & oncology 20181006
<h4>Background</h4>Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy characterized by neoplastic cells that are positive for CD123, CD4, BDCA2, and TCL1 and aberrant expression of CD56. Historically, patients with BPDCN have an unfavorable prognosis and the optimal treatment is not established due to lack of prospective data.<h4>Case report</h4>In this report we describe a patient with Felty's syndrome and myelodysplastic syndrome (MDS) in whom ...[more]