Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC6174795 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Li Xinyu X Meng Qiang Q Zhang Lei L
Journal of immunology research 20180923
Pancreatic islet transplantation as a therapeutic option for type 1 diabetes mellitus is gaining widespread attention because this approach can restore physiological insulin secretion, minimize the risk of hypoglycemic unawareness, and reduce the risk of death due to severe hypoglycemia. However, there are many obstacles contributing to the early mass loss of the islets and progressive islet loss in the late stages of clinical islet transplantation, including hypoxia injury, instant blood-mediat ...[more]