Ontology highlight
ABSTRACT:
SUBMITTER: Sideras K
PROVIDER: S-EPMC6175125 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Sideras Kostandinos K Galjart Boris B Vasaturo Angela A Pedroza-Gonzalez Alexander A Biermann Katharina K Mancham Shanta S Nigg Alex L AL Hansen Bettina E BE Stoop Hans A HA Zhou Guoying G Verhoef Cornelis C Sleijfer Stefan S Sprengers Dave D Kwekkeboom Jaap J Bruno Marco J MJ
Journal of surgical oncology 20180607 1
<h4>Background and objectives</h4>Patients with isolated colorectal-cancer-liver-metastases (CRCLM) frequently undergo metastatectomy. Tumor-infiltrating-lymphocytes (TILs) have prognostic potential in the setting of primary colorectal cancer, however, their role in CRCLM is less studied. We aimed to study the spatial distribution and prognostic role of tumor-infiltrating CD8<sup>+</sup> cytotoxic T-cells and FoxP3<sup>+</sup> regulatory T-cells at the metastatic site of CRCLM patients.<h4>Metho ...[more]