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ABSTRACT:
SUBMITTER: Adler P
PROVIDER: S-EPMC6175129 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Adler Pauline P Pons Amandine A Li Jing J Heider Jörg J Brutiu Bogdan R BR Maulide Nuno N
Angewandte Chemie (International ed. in English) 20180911 40
Phosphonates have garnered considerable attention for years owing to both their singular biological properties and their synthetic potential. State-of-the-art methods for the preparation of mixed phosphonates, phosphonamidates, phosphonothioates, and phosphinates rely on harsh and poorly selective reaction conditions. We report herein a mild method for the modular preparation of phosphonylated derivatives, several of which exhibit interesting biological activities, that is based on chemoselectiv ...[more]