Ontology highlight
ABSTRACT:
SUBMITTER: Cerdeira AS
PROVIDER: S-EPMC6175139 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Cerdeira A S AS Agrawal S S Staff A C AC Redman C W CW Vatish M M
BJOG : an international journal of obstetrics and gynaecology 20171228 11
Pre-eclampsia is a complex disease with significant maternal and fetal morbidity and mortality. Its syndromic nature makes diagnosis and management difficult. The field is rapidly evolving with the definition of pre-eclampsia being challenged by some organisations, with proteinuria no longer being essential in the presence of other features. In the last decade, angiogenic factors, in particular soluble fms-like tyrosine kinase 1 (sFlt-1), have emerged as important molecules in the pathogenesis o ...[more]