Ontology highlight
ABSTRACT:
SUBMITTER: Klinger R
PROVIDER: S-EPMC6175283 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Klinger Regine R Stuhlreyer Julia J Schwartz Marie M Schmitz Julia J Colloca Luana L
International review of neurobiology 20180806
The analgesic placebo effect is well documented by numerous studies. Many important influencing factors, however, are yet to be discovered. In the arena of placebo effects and clinical implications, expectancies play a central role. Expectancies are shaped by processes of classical and social learning as well as verbal instructions and are strongly related to emotional factors. Expectancies trigger a cascade of endogenous opioids and non-opioids, which alter the experience of pain. For clinical ...[more]