Ontology highlight
ABSTRACT:
SUBMITTER: Aleku GA
PROVIDER: S-EPMC6175315 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Aleku Godwin A GA Prause Christoph C Bradshaw-Allen Ruth T RT Plasch Katharina K Glueck Silvia M SM Bailey Samuel S SS Payne Karl A P KAP Parker David A DA Faber Kurt K Leys David D
ChemCatChem 20180717 17
Fungal ferulic acid decarboxylases (FDCs) belong to the UbiD-family of enzymes and catalyse the reversible (de)carboxylation of cinnamic acid derivatives through the use of a prenylated flavin cofactor. The latter is synthesised by the flavin prenyltransferase UbiX. Herein, we demonstrate the applicability of FDC/UbiX expressing cells for both isolated enzyme and whole-cell biocatalysis. FDCs exhibit high activity with total turnover numbers (TTN) of up to 55000 and turnover frequency (TOF) of u ...[more]