Effect of Vitamin D Supplementation on Obesity-Induced Insulin Resistance: A Double-Blind, Randomized, Placebo-Controlled Trial.
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ABSTRACT:
SUBMITTER: Cefalo CMA
PROVIDER: S-EPMC6175391 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
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Effect of Vitamin D Supplementation on Obesity-Induced Insulin Resistance: A Double-Blind, Randomized, Placebo-Controlled Trial.
Cefalo Chiara M A CMA Conte Caterina C Sorice Gian Pio GP Moffa Simona S Sun Vinsin A VA Cinti Francesca F Salomone Enrica E Muscogiuri Giovanna G Brocchi Alex A G AAG Pontecorvi Alfredo A Mezza Teresa T Giaccari Andrea A
Obesity (Silver Spring, Md.) 20180304 4
<h4>Objective</h4>The aim was to investigate whether vitamin D supplementation, combined with a hypocaloric diet, could have an independent effect on insulin sensitivity in subjects with both overweight and hypovitaminosis D. Changes from baseline in anthropometric parameters, body composition, glucose tolerance, and insulin secretion were considered as secondary outcomes.<h4>Methods</h4>Eighteen volunteers who were nondiabetic and vitamin D deficient and had BMI > 25 kg/m<sup>2</sup> were rando ...[more]
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