Ontology highlight
ABSTRACT:
SUBMITTER: Sikes KJ
PROVIDER: S-EPMC6175639 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Sikes Katie J KJ Li Jun J Gao Shu-Guang SG Shen Quan Q Sandy John D JD Plaas Anna A Wang Vincent M VM
Connective tissue research 20180606 5
Purpose/Aim of the study: Healthy tendons are maintained in homeostasis through controlled usage of glucose for energy and redox equilibrium. Tendon cell stress imposed by overuse injury or vascular insufficiency is accompanied by activation of wound healing pathways which facilitate an adaptive response and the restoration of homeostasis. To understand this response at the gene expression level we have studied the in vivo effects of injected TGF-β1 in a murine model of tendinopathy, as well as ...[more]