Ontology highlight
ABSTRACT:
SUBMITTER: Pinto C
PROVIDER: S-EPMC6175958 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Pinto Cecilia C Mance Deni D Sinnige Tessa T Daniëls Mark M Weingarth Markus M Baldus Marc M
Nature communications 20181008 1
The β-barrel assembly machinery (BAM) is a pentameric complex (BamA-E), which catalyzes the essential process of β-barrel protein insertion into the outer membrane of E. coli. Thus far, a detailed understanding of the insertion mechanism has been elusive but recent results suggest that local protein motion, in addition to the surrounding membrane environment, may be of critical relevance. We have devised a high-sensitivity solid-state NMR approach to directly probe protein motion and the structu ...[more]