VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons.
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ABSTRACT:
SUBMITTER: Wozny C
PROVIDER: S-EPMC6176088 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons.
Wozny Christian C Beed Prateep P Nitzan Noam N Pössnecker Yona Y Rost Benjamin R BR Schmitz Dietmar D
Frontiers in cellular neuroscience 20181002
The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis. ...[more]
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