Ontology highlight
ABSTRACT:
SUBMITTER: Ishimura ME
PROVIDER: S-EPMC6177168 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ishimura Mayari E ME Teixeira Daniela D Silveira Gabriela da P GDP Gambero Mônica M Gama Gabriel A C GAC Pimenta Bruna S O BSO Rodrigues Elaine G EG Longo-Maugéri Ieda M IM
PloS one 20181009 10
Hybrid vaccines have been investigated in clinical and experimental studies once expresses total antigens of a tumor cell combined with the ability of a dendritic cell (DC) to stimulate immune responses. However, the response triggered by these vaccines is often weak, requiring the use of adjuvants to increase vaccine immunogenicity. Killed Propionibacterium acnes (P. acnes) exerts immunomodulatory effects by increasing the phagocytic and tumoricidal activities of macrophages, promoting DC matur ...[more]