Ontology highlight
ABSTRACT:
SUBMITTER: Faizy TD
PROVIDER: S-EPMC6177453 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Scientific reports 20181009 1
Myelin Water Fraction (MWF) measurements derived from quantitative Myelin Water Imaging (MWI) may detect demyelinating changes of the cerebral white matter (WM) microstructure. Here, we investigated age-related alterations of the MWF in normal aging brains of healthy volunteers utilizing two fast and clinically feasible 3D gradient and spin echo (GRASE) MWI sequences with 3 mm and 5 mm isotropic voxel size. In 45 healthy subjects (age range: 18-79 years), distinct regions of interest (ROI) were ...[more]