Ontology highlight
ABSTRACT:
SUBMITTER: Yale AR
PROVIDER: S-EPMC6178213 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Yale Andrew R AR Nourse Jamison L JL Lee Kayla R KR Ahmed Syed N SN Arulmoli Janahan J Jiang Alan Y L AYL McDonnell Lisa P LP Botten Giovanni A GA Lee Abraham P AP Monuki Edwin S ES Demetriou Michael M Flanagan Lisa A LA
Stem cell reports 20180906 4
Understanding the cellular properties controlling neural stem and progenitor cell (NSPC) fate choice will improve their therapeutic potential. The electrophysiological measure whole-cell membrane capacitance reflects fate bias in the neural lineage but the cellular properties underlying membrane capacitance are poorly understood. We tested the hypothesis that cell surface carbohydrates contribute to NSPC membrane capacitance and fate. We found NSPCs differing in fate potential express distinct p ...[more]