Ontology highlight
ABSTRACT:
SUBMITTER: Meira T
PROVIDER: S-EPMC6178349 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Meira Torcato T Leroy Felix F Buss Eric W EW Oliva Azahara A Park Jung J Siegelbaum Steven A SA
Nature communications 20181009 1
Recent results suggest that social memory requires the dorsal hippocampal CA2 region as well as a subset of ventral CA1 neurons. However, it is unclear whether dorsal CA2 and ventral CA1 represent parallel or sequential circuits. Moreover, because evidence implicating CA2 in social memory comes largely from long-term inactivation experiments, the dynamic role of CA2 in social memory remains unclear. Here, we use pharmacogenetics and optogenetics in mice to acutely and reversibly silence dorsal C ...[more]