Dataset Information
Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson's Disease.
Ontology highlight
ABSTRACT: Background and methods
To investigate the possible efficacy of an elastic abdominal binder to control orthostatic hypotension (OH) associated with Parkinson's disease (PD), 15 patients with PD and OH were enrolled in a single-blind crossover study with elastic abdominal versus placebo binder on two different days, separated by a 1-day interval, followed by a 4-week open-label follow-up.Results
Intervention significantly reduced blood pressure fall upon tilting. The mean difference (standard deviation; 95% confidence intervals) between abdominal binder versus placebo was +10 mm Hg (10.2; +3.5, +16.5; P = 0.006). No significant effect on supine mean blood pressure values was observed compared to placebo (P = 0.3). Symptoms of OH decreased significantly during follow-up (P = 0.003), as assessed by means of the Orthostatic Hypotension Questionnaire.Conclusions
Our findings suggest that elastic abdominal binders may be a simple complementary tool to alleviate OH in PD.
SUBMITTER: Fanciulli A
PROVIDER: S-EPMC6178725 | biostudies-literature | 2016 Mar-Apr
REPOSITORIES: biostudies-literature
Publications
Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson's Disease.
Movement disorders clinical practice 20151127 2
<h4>Background and methods</h4>To investigate the possible efficacy of an elastic abdominal binder to control orthostatic hypotension (OH) associated with Parkinson's disease (PD), 15 patients with PD and OH were enrolled in a single-blind crossover study with elastic abdominal versus placebo binder on two different days, separated by a 1-day interval, followed by a 4-week open-label follow-up.<h4>Results</h4>Intervention significantly reduced blood pressure fall upon tilting. The mean differenc ...[more]