Ontology highlight
ABSTRACT:
SUBMITTER: Co JY
PROVIDER: S-EPMC6180003 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Co Julia Y JY Cárcamo-Oyarce Gerardo G Billings Nicole N Wheeler Kelsey M KM Grindy Scott C SC Holten-Andersen Niels N Ribbeck Katharina K
NPJ biofilms and microbiomes 20181010
Mucus is a biological gel that lines all wet epithelia in the body, including the mouth, lungs, and digestive tract, and has evolved to protect the body from pathogenic infection. However, microbial pathogenesis is often studied in mucus-free environments that lack the geometric constraints and microbial interactions in physiological three-dimensional mucus gels. We developed fluid-flow and static test systems based on purified mucin polymers, the major gel-forming constituents of the mucus barr ...[more]