Ontology highlight
ABSTRACT:
SUBMITTER: Saunders CT
PROVIDER: S-EPMC6180946 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Saunders Christina T CT Blume Jeffrey D JD
Biostatistics (Oxford, England) 20181001 4
Mediation analysis explores the degree to which an exposure's effect on an outcome is diverted through a mediating variable. We describe a classical regression framework for conducting mediation analyses in which estimates of causal mediation effects and their variance are obtained from the fit of a single regression model. The vector of changes in exposure pathway coefficients, which we named the essential mediation components (EMCs), is used to estimate standard causal mediation effects. Becau ...[more]