Ontology highlight
ABSTRACT:
SUBMITTER: Brettschneider J
PROVIDER: S-EPMC6181179 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Brettschneider Johannes J Suh EunRan E Robinson John L JL Fang Lubin L Lee Edward B EB Irwin David J DJ Grossman Murray M Van Deerlin Vivianna M VM Lee Virginia M-Y VM Trojanowski John Q JQ
Journal of neuropathology and experimental neurology 20181101 11
We aimed to determine patterns of α-synuclein (α-syn) pathology in multiple system atrophy (MSA) using 70-µm-thick sections of 20 regions of the central nervous system of 37 cases with striato-nigral degeneration (SND) and 10 cases with olivo-ponto-cerebellar atrophy (OPCA). In SND cases with the shortest disease duration (phase 1), α-syn pathology was observed in striatum, lentiform nucleus, substantia nigra, brainstem white matter tracts, cerebellar subcortical white matter as well as motor co ...[more]