Ontology highlight
ABSTRACT:
SUBMITTER: Miskinyte G
PROVIDER: S-EPMC6181302 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
PloS one 20181011 10
Human neurodegenerative disorders affect specific types of cortical neurons. Efficient protocols for the generation of such neurons for cell replacement, disease modeling and drug screening are highly warranted. Current methods for the production of cortical neurons from human embryonic stem (ES) cells are often time-consuming and inefficient, and the functional properties of the generated cells have been incompletely characterized. Here we have used transcription factor (TF) programming with th ...[more]