CAN GENETIC VARIANTS UNDERLYING SUBJECTIVE WELL-BEING PREDICT AGE-RELATED HEALTH PROBLEMS?
Ontology highlight
ABSTRACT:
SUBMITTER: Mosing M
PROVIDER: S-EPMC6185070 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Similar Datasets
Project description:Parenthood, marital status and social networks have been shown to relate to the well-being and mental health of older people. Using a large sample of respondents aged 50 and older from 16 European countries, we identify the associations of well-being and mental health with family status. Making use of detailed social network data of the respondents, we also identify how different social support networks correlate with the well-being and health indicators. We observe positive associations for all network types, over and beyond any direct associations of family status with well-being. Results suggest that non-residential children are important providers of social support for their parents at older age.
| S-EPMC6656342 | biostudies-literature
Project description:BackgroundThe psychological importance of subjective well-being for a healthy life has been well recognized. It is also well known that depressive and anxiety disorders have a negative effect on subjective well-being. The aim of this cross-sectional, descriptive study was to assess the subjective well-being status of a group of primary healthcare patients in relation to socio-demographic characteristics, personal health and mood-status.MethodsA total of 284 patients participated in the study. The Oxford Happiness Scale, Life Satisfaction Scale, DASS-42 (Depression, Anxiety and Stress Scales-42) and a questionnaire about socio-demographic characteristics were completed by the participants.ResultsIn general, the participants were found to be moderately happy and satisfied with their lives. They had mild levels of depression, anxiety and stress. In terms of happiness, an older age (?40 years), educated to secondary level or higher and not having depression or anxiety were found to be factors increasing happiness. In terms of life satisfaction, female gender, an older age (?40 years), educated to secondary level or higher, being single and not having depression were found to increase life satisfaction.ConclusionPrimary healthcare providers should give more importance to the mood status of their patients. Screening for depression and anxiety should be applied at the primary healthcare level because negative mood status is more important than some socio-demographic characteristics in respect of unhappiness and dissatisfaction.
| S-EPMC4259359 | biostudies-literature
Project description:In this paper we analyze the relationship between turnover-driven growth and subjective wellbeing. Our model of innovation-led growth and unemployment predicts that: (i) the effect of creative destruction on expected individual welfare should be unambiguously positive if we control for unemployment, less so if we do not; (ii) job creation has a positive and job destruction has a negative impact on wellbeing; (iii) job destruction has a less negative impact in US Metropolitan Statistical Areas (MSA) within states with more generous unemployment insurance policies; (iv) job creation has a more positive effect on individuals that are more forward-looking. The empirical analysis using cross-sectional MSA-level and individual-level data provide empirical support to these predictions.
| S-EPMC5510036 | biostudies-literature
Project description:Subjective well-being (SWB) is a major topic of research across the social sciences. Twin and family studies have found that genetic factors may account for as much as 30-40% of the variance in SWB. Here, we study genetic contributions to SWB in a pooled sample of ? 11,500 unrelated, comprehensively-genotyped Swedish and Dutch individuals. We apply a recently developed method to estimate "common narrow heritability": the fraction of variance in SWB that can be explained by the cumulative additive effects of genetic polymorphisms that are common in the population. Our estimates are 5-10% for single-question survey measures of SWB, and 12-18% after correction for measurement error in the SWB measures. Our results suggest guarded optimism about the prospects of using genetic data in SWB research because, although the common narrow heritability is not large, the polymorphisms that contribute to it could feasibly be discovered with a sufficiently large sample of individuals.
| S-EPMC3683731 | biostudies-literature
Project description:Previous research has overlooked the heterogeneity in older adults' personal conceptions of subjective well-being (SWB), by not taking into account intradomain differences in the conceptions of SWB for different groups of older adults. The aim of this article is therefore to explore (a) older adults' own views on which aspects, categorized under domains, are important to their SWB and (b) which domains and aspects are important to older adults in different contexts and with different characteristics: to men and women, of different ages, and in different housing arrangements.Sixty-six older adults (aged 65 and older) participated in our study. We asked the participants to freely nominate aspects of SWB that are important to them, using participant-generated word clouds as our exploratory, qualitative data collection method. The data were analyzed using qualitative inductive content analysis.We found 15 domains based on our participants' conceptions of SWB. The multidimensional domains of social life, activities, health, and space and place were most important to our participants. The domains and aspects were defined and prioritized differently by different groups of participants.SWB should be studied as a multidimensional, individualized, and contextualized process to generate meaningful empirical information for researchers and policymakers.
| S-EPMC5434489 | biostudies-literature
Project description:Although it is known that health is not merely the absence of disease, the positive aspects of mental health have been less comprehensively researched compared with its negative aspects. Subjective well-being (SWB) is one of the indicators of positive psychology, and high SWB is considered to benefit individuals in multiple ways. However, the neural mechanisms underlying individual differences in SWB remain unclear, particularly in terms of brain microstructural properties as detected by diffusion tensor imaging. The present study aimed to investigate the relationship between measurements of diffusion tensor imaging [mean diffusivity (MD) and fractional anisotropy] and the degree of SWB as measured using a questionnaire. Voxel-based analysis was used to investigate the association between MD and SWB scores in healthy young adults (age, 20.7 ± 1.8 years; 695 males and 514 females). Higher levels of SWB were found to be associated with lower MD in areas surrounding the right putamen, insula, globus pallidus, thalamus and caudate. These results indicated that individual SWB is associated with variability in brain microstructural properties.
| S-EPMC8483277 | biostudies-literature
Project description:ObjectivesThis study examined whether oral health is a neglected aspect of subjective well-being (SWB) among older adults. The key research question was whether deterioration in oral health among dentate older adults living in England was associated with decreases in SWB, using measures of eudemonic, evaluative, and affective dimensions of well-being.MethodsThis secondary analysis used data from the third (2006-2007) and fifth (2010-2011) waves of respondents aged 50 and older from the English Longitudinal Study of Ageing (ELSA). We fitted multivariable regression models to examine the effects of changes in oral impacts on daily life and edentulism (complete tooth loss) on SWB (quality of life, life satisfaction, and depressive symptomatology).ResultsA worsening in both oral health measures was associated with an increase in depressive symptoms even after adjusting for time-varying confounders including declining health, activities of daily living, and reduced social support. Becoming edentate was also associated with decreases in quality of life and life satisfaction.DiscussionA deterioration in oral health and oral health-related quality of life increases the risk of depressive symptoms among older adults and highlights the importance of oral health as a determinant of subjective well-being in later life.
| S-EPMC5927002 | biostudies-literature
Project description:This study addresses the links between different dimensions of intergenerational family relations (solidarity, conflict, and ambivalence) and subjective well-being (life satisfaction, and positive and negative affects) of older people (aged 75+) using a comparative perspective from a random urban sample in five countries (Norway, England, Germany, Spain, and Israel). Comparative descriptive analyses and multivariate models are presented. Three general conclusions can be drawn. First, the country variables contributed significantly to the explained variance for all three components of well-being, where Israel was most different from the other four countries, except for positive affects, for which Spain and Israel differed from Norway, England, and Germany. However, the countries explained more of the variance for positive and negative affects compared with life satisfaction. Second, the intergenerational family solidarity dimensions contributed significantly to the explained variance for all three components of well-being, although they were differentially related to the different aspects of subjective well-being. Third, personal resources, mainly physical functioning and financial adequacy, were related to all of the well-being variables, although their relative contribution was much stronger for life satisfaction. The importance of intergenerational family relations and personal resources for the subjective well-being of older people and the importance of using multiple measures for outcome variables of well-being are discussed.
| S-EPMC5547300 | biostudies-other
Project description:Despite the importance of subjective well-being (SWB) for students' mental and physical health, there is a lack of longitudinal studies investigating the development of SWB in adolescents and what factors are associated with it over time. The present study seeks to shed further light on this question by investigating adolescents longitudinally. A sample of German academic tracks students (N = 476) from five schools were followed longitudinally over a time period of 30 months with four measurement points from Grade 11 to Grade 13. Alongside the longitudinal assessment of SWB (mood and life satisfaction), a range of other factors were also assessed at t1 including; demographic factors (sex, age, socio-economic status (HISEI)), intelligence, grades (report cards provided by the schools), personality (neuroticism, extraversion) and perceived parental expectations and support. Latent growth curve models were conducted to investigate the development of SWB and its correlates. On average, mood and life satisfaction improved at the end of mandatory schooling. However, students significantly differed in this pattern of change. Students' life satisfaction developed more positively if students had good grades at t1. Furthermore, even though introverted students started with lower life satisfaction at t1, extraverts' life showed greater increases over time. Changes in mood were associated with socio-economic background; the higher the HISEI the more positive the change. As social comparisons in school performance are almost inevitable, schools should intervene to buffer the influence of school grades on students' SWB.
| S-EPMC6801746 | biostudies-literature
Project description:There is now recognition that a population's overall level of well-being is defined not just by income and wealth. Where we live and who we interact with are likely to be equally important in our overall levels of satisfaction with our lives. This thinking has stimulated studies of subjective well-being, or happiness, at both national and local scales. These studies suggest that where you live does matter, although it is health and family status that have the most direct effects on well-being. In this study, we use a detailed dataset on well-being from the China Household Finance Survey to reexamine well-being across China, where profound socioeconomic changes are taking place. The study controls for self-reported health and examines subjective well-being across extensive and varied Chinese urban and rural environments. We find that the earlier pessimism about China's well-being, which emphasized declining happiness, may be misplaced. We make two contributions: first, we show a rising level of subjective well-being, and second, we show that there is a narrowing gap in well-being across different social indicators. Methodologically, we bring in the perspectives of both social capital and geographic context.
| S-EPMC6708306 | biostudies-literature