Ontology highlight
ABSTRACT:
SUBMITTER: Dai D
PROVIDER: S-EPMC6186775 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Dai Daofeng D Pu Tianning T Liang Jingdan J Wang Zhijun Z Tang Aifa A
Frontiers in microbiology 20181008
DNA sulfur modification is a unique modification occurring in the sugar-phosphate backbone of DNA, with a nonbridging oxygen atom substituted with sulfur in a sequence-specific and <i>R</i>p stereo-specific manner. Bioinformatics, RNA-seq, and <i>in vitro</i> transcriptional analyses have shown that DNA sulfur modification may be involved in epigenetic regulation. However, the <i>in vivo</i> evidence supporting this assertion is not convincing. Here, we aimed to characterize two sulfur-modified ...[more]