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Management of recurrent pleural mesothelioma: Successful rechallenge with nintedanib in combination with chemotherapy.


ABSTRACT: Malignant pleural mesothelioma (MPM) is a rare neoplasm, generally caused by asbestos exposure. This case details how a patient treated with nintedanib during the LUME-Meso study was rechallenged with nintedanib. The findings highlight the benefit of nintedanib rechallenge and the potential use of continuous anti-angiogenic therapy in MPM treatment.

SUBMITTER: Grosso F 

PROVIDER: S-EPMC6186873 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Management of recurrent pleural mesothelioma: Successful rechallenge with nintedanib in combination with chemotherapy.

Grosso Federica F   Roveta Annalisa A   Gallizzi Giulia G   Belletti Marco M  

Clinical case reports 20180904 10


Malignant pleural mesothelioma (MPM) is a rare neoplasm, generally caused by asbestos exposure. This case details how a patient treated with nintedanib during the LUME-Meso study was rechallenged with nintedanib. The findings highlight the benefit of nintedanib rechallenge and the potential use of continuous anti-angiogenic therapy in MPM treatment. ...[more]

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