Ontology highlight
ABSTRACT:
SUBMITTER: Chernov MM
PROVIDER: S-EPMC6187135 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Chernov Mykyta M MM Friedman Robert M RM Chen Gang G Stoner Gene R GR Roe Anna Wang AW
Proceedings of the National Academy of Sciences of the United States of America 20180926 41
In primates, visual perception is mediated by brain circuits composed of submillimeter nodes linked together in specific networks that process different types of information, such as eye specificity and contour orientation. We hypothesized that optogenetic stimulation targeted to cortical nodes could selectively activate such cortical networks. We used viral transfection methods to confer light sensitivity to neurons in monkey primary visual cortex. Using intrinsic signal optical imaging and sin ...[more]