Unknown

Dataset Information

0

Formation of Branched and Chained Alginate Microfibers Using Theta-Glass Capillaries.


ABSTRACT: This study proposes a microfluidic spinning method to form alginate microfibers with branched and chained structures by controlling two streams of a sodium alginate solution extruded from a theta-glass capillary (a double-compartmented glass capillary). The two streams have three flow regimes: (i) a combined flow regime (single-threaded stream), (ii) a separated flow regime (double-threaded stream), and (iii) a chained flow regime (stream of repeating single- and double-threaded streams). The flow rate of the sodium alginate solution and the tip diameter of the theta-glass capillary are the two parameters which decide the flow regime. By controlling the two parameters, we form branched (a Y-shaped structure composed of thick parent fiber and permanently divided two thin fibers) and chained (a repeating structure of single- and double-threaded fibers with constant frequency) alginate microfibers with various dimensions. Furthermore, we demonstrate the applicability of the alginate microfibers as sacrificial templates for the formation of chain-shaped microchannels with two inlets. Such microchannels could mimic the structure of blood vessels and are applicable for the research fields of fluidics including hemodynamics.

SUBMITTER: Nishimura K 

PROVIDER: S-EPMC6187737 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Formation of Branched and Chained Alginate Microfibers Using Theta-Glass Capillaries.

Nishimura Keigo K   Morimoto Yuya Y   Mori Nobuhito N   Takeuchi Shoji S  

Micromachines 20180617 6


This study proposes a microfluidic spinning method to form alginate microfibers with branched and chained structures by controlling two streams of a sodium alginate solution extruded from a theta-glass capillary (a double-compartmented glass capillary). The two streams have three flow regimes: (i) a combined flow regime (single-threaded stream), (ii) a separated flow regime (double-threaded stream), and (iii) a chained flow regime (stream of repeating single- and double-threaded streams). The fl  ...[more]

Similar Datasets

| S-EPMC4165459 | biostudies-literature
| S-EPMC5456451 | biostudies-literature
| S-EPMC4303338 | biostudies-other
| S-EPMC9268077 | biostudies-literature
| S-EPMC8313020 | biostudies-literature
| S-EPMC4138999 | biostudies-literature
| S-EPMC3731149 | biostudies-literature
| S-EPMC10393589 | biostudies-literature
| S-EPMC4735709 | biostudies-literature
| S-EPMC7310267 | biostudies-literature