Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC6188473 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
eLife 20181015
Determination of the molecular properties of genetically targeted cell types has led to fundamental insights into mouse brain function and dysfunction. Here, we report an efficient strategy for precise exploration of gene expression and epigenetic events in specific cell types in a range of species, including postmortem human brain. We demonstrate that classically defined, homologous neuronal and glial cell types differ between rodent and human by the expression of hundreds of orthologous, cell ...[more]