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A Robot-Assisted Cell Manipulation System with an Adaptive Visual Servoing Method.


ABSTRACT: Robot-assisted cell manipulation is gaining attention for its ability in providing high throughput and high precision cell manipulation for the biological industry. This paper presents a visual servo microrobotic system for cell microinjection. We investigated the automatic cell autofocus method that reduced the complexity of the system. Then, we produced an adaptive visual processing algorithm to detect the location of the cell and micropipette toward the uneven illumination problem. Fourteen microinjection experiments were conducted with zebrafish embryos. A 100% success rate was achieved either in autofocus or embryo detection, which verified the robustness of the proposed automatic cell manipulation system.

SUBMITTER: Xie Y 

PROVIDER: S-EPMC6190104 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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A Robot-Assisted Cell Manipulation System with an Adaptive Visual Servoing Method.

Xie Yu Y   Zeng Feng F   Xi Wenming W   Zhou Yunlei Y   Liu Houde H   Chen Mingliang M  

Micromachines 20160620 6


Robot-assisted cell manipulation is gaining attention for its ability in providing high throughput and high precision cell manipulation for the biological industry. This paper presents a visual servo microrobotic system for cell microinjection. We investigated the automatic cell autofocus method that reduced the complexity of the system. Then, we produced an adaptive visual processing algorithm to detect the location of the cell and micropipette toward the uneven illumination problem. Fourteen m  ...[more]

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