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ABSTRACT: Background
Surgical-site infection (SSI) is associated with significant healthcare costs. To reduce the high rate of SSI among patients undergoing colorectal surgery at a cancer centre, a comprehensive care bundle was implemented and its efficacy tested.Methods
A pragmatic study involving three phases (baseline, implementation and sustainability) was conducted on patients treated consecutively between 2013 and 2016. The intervention included 13 components related to: bowel preparation; oral and intravenous antibiotic selection and administration; skin preparation, disinfection and hygiene; maintenance of normothermia during surgery; and use of clean instruments for closure. SSI risk was evaluated by means of a preoperative calculator, and effectiveness was assessed using interrupted time-series regression.Results
In a population with a mean BMI of 30?kg/m2 , diabetes mellitus in 17·5 per cent, and smoking history in 49·3 per cent, SSI rates declined from 11·0 to 4·1 per cent following implementation of the intervention bundle (P?= 0·001). The greatest reductions in SSI rates occurred in patients at intermediate or high risk of SSI: from 10·3 to 4·7 per cent (P?=?0·006) and from 19 to 2 per cent (P?ConclusionMeaningful reductions in SSI can be achieved by implementing a multidisciplinary care bundle at a hospital-wide level.
SUBMITTER: Weiser MR
PROVIDER: S-EPMC6190910 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Weiser M R MR Gonen M M Usiak S S Pottinger T T Samedy P P Patel D D Seo S S Smith J J JJ Guillem J G JG Temple L L Nash G M GM Paty P B PB Baldwin-Medsker A A Cheavers C E CE Eagan J J Garcia-Aguilar J J
The British journal of surgery 20180704 12
<h4>Background</h4>Surgical-site infection (SSI) is associated with significant healthcare costs. To reduce the high rate of SSI among patients undergoing colorectal surgery at a cancer centre, a comprehensive care bundle was implemented and its efficacy tested.<h4>Methods</h4>A pragmatic study involving three phases (baseline, implementation and sustainability) was conducted on patients treated consecutively between 2013 and 2016. The intervention included 13 components related to: bowel prepar ...[more]