Ontology highlight
ABSTRACT:
SUBMITTER: Hughes MP
PROVIDER: S-EPMC6192703 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20180201 6376
Subcellular membraneless assemblies are a reinvigorated area of study in biology, with spirited scientific discussions on the forces between the low-complexity protein domains within these assemblies. To illuminate these forces, we determined the atomic structures of five segments from protein low-complexity domains associated with membraneless assemblies. Their common structural feature is the stacking of segments into kinked β sheets that pair into protofilaments. Unlike steric zippers of amyl ...[more]