Menopausal symptoms and risk of coronary heart disease in middle-aged women: A nationwide population-based cohort study.

ABSTRACT:

Objective

To assess the relationship between coronary heart disease (CHD) and menopausal symptoms in middle-aged women in Taiwan.

Patients and methods

The present study identified 14,340 symptomatic menopausal women without a history of CHD from the Taiwan National Health Insurance Research Database from January 1, 2000, to December 31, 2013. A total of 14,340 age- and Charlson-comorbidity-index-score-matched asymptomatic women were used as controls. Possible comorbidity-attributable risks of CHD were surveyed to assess whether the symptomatic menopausal cohort had a higher incidence of CHD.

Results

The incidence of CHD was higher in the symptomatic menopausal cohort than in the control cohort (17.18 vs. 12.05 per 1000 person-years). After adjustment in multivariate C

SUBMITTER: Huang CH 

PROVIDER: S-EPMC6193730 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature