Ontology highlight
ABSTRACT:
SUBMITTER: Braun LR
PROVIDER: S-EPMC6194811 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Braun Laurie R LR Feldpausch Meghan N MN Czerwonka Natalia N Weiss Julian J Branch Karen K Lee Hang H Martinez-Salazar Edgar L EL Torriani Martin M Sponseller Craig A CA Grinspoon Steven K SK Stanley Takara L TL
The Journal of clinical endocrinology and metabolism 20181101 11
<h4>Context</h4>3-Hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins) are widely prescribed. Statins may have important metabolic effects on insulin sensitivity and liver fat, but limited studies have assessed these effects by using euglycemic hyperinsulinemic clamp, stable isotopes, and 1H magnetic resonance spectroscopy (MRS) for liver fat quantification.<h4>Objective</h4>To study the effects of pitavastatin on hepatic fat and insulin sensitivity.<h4>Design</h4>Six-month, doubl ...[more]