Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC6195336 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Wang Z Z Lee W J WJ Koh B T H BTH Hong M M Wang W W Lim P N PN Feng J J Park L S LS Kim M M Thian E S ES
Science advances 20181019 10
Structural and hierarchical anisotropy underlies the structure-function relationship of most living tissues. Attempts to exploit the interplay between cells and their immediate environment have rarely featured macroscale, three-dimensional constructs required for clinical applications. Furthermore, compromises to biomechanical robustness during fabrication often limit the scaffold's relevance in translational medicine. We report a polymeric three-dimensional scaffold with tendon-like mechanical ...[more]